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Validation for WT, Q357R, and het IKs. Experiments are from Boulet et al8 (squares: WT is black, Q357R is white, and het is gray). A: Steady-state activation of tail currents. B: Time constant for step current activation. C: Time constant for deactivation. D: Relative current, after 5-second steps to the potentials shown along the abscissa. Simulated protocols were the same as those used in Boulet experiments. Exp, experiments; sims, simulations. het = heterozygous; WT = wild type.
