Table 3.
Significance of ErbB receptor family as a marker for bladder cancer death.
| Study name | Methods | Pts no. | Study subject | Significance |
|---|---|---|---|---|
| EGFR | ||||
| [13] | IHC | 73 | T2–4 | Yes |
| [25] | IHC | 109 | T2 | NS |
| [16] | IHC | 182 | T0–4 | NS |
| [26] | IHC | 59 | T2–4 | Yes |
| [27] | IHC | 141 | T2–4 | NS |
| [15] | IHC | 52 | T0-1 | NS |
| IHC | 101 | T0–4 | Yes | |
| [26] | RT-PCR | 59 | T2–4 | Yes |
| [28] | RT-PCR | 88 | T0–4 | NS |
| [29] | qRT-PCR | 73 | T0–4 | NS |
|
| ||||
| ErbB2 | ||||
| [30] | Gene amplification | 163 | T0–4 | Yes |
| [31] | Gene amplification | 57 | T0–4 | Yes |
| [21] | FISH | 62 | T0–4 | NS |
| [32] | FISH | 1500 | T0–4 | NS |
| [13] | IHC | 55 | T2–4 | NS |
| [22] | IHC | 39 | T3-4 | Yes |
| [25] | IHC | 109 | T2 | NS |
| [33] | IHC | 80 | T2–4 | NS |
| [16] | IHC | 184 | T0–4 | NS |
| [34] | IHC | 90 | T2–4 | Yes |
| [35] | IHC | 138 | T2–4 | Yes |
| [36] | IHC | 132 | T2–4 | Yes |
| [27] | IHC | 141 | T2–4 | NS |
| [37] | IHC | 88 | T0–4 | Yes |
| [32] | IHC | 1500 | T0–4 | NS |
| [5] | IHC | 245 | T0–4 | Yes |
| [23] | IHC | 89 | T0–4 | Yes |
| [28] | RT-PCR | 88 | T0–4 | NS |
| [29] | RT-PCR | 73 | T0–4 | NS |
|
| ||||
| ErbB3 or ErbB4 | ||||
| [16] |
IHC | 128 | T0–4 | NS |
| IHC | 124 | T0–4 | Yes | |