Table 3.
Study name | Methods | Pts no. | Study subject | Significance |
---|---|---|---|---|
EGFR | ||||
[13] | IHC | 73 | T2–4 | Yes |
[25] | IHC | 109 | T2 | NS |
[16] | IHC | 182 | T0–4 | NS |
[26] | IHC | 59 | T2–4 | Yes |
[27] | IHC | 141 | T2–4 | NS |
[15] | IHC | 52 | T0-1 | NS |
IHC | 101 | T0–4 | Yes | |
[26] | RT-PCR | 59 | T2–4 | Yes |
[28] | RT-PCR | 88 | T0–4 | NS |
[29] | qRT-PCR | 73 | T0–4 | NS |
| ||||
ErbB2 | ||||
[30] | Gene amplification | 163 | T0–4 | Yes |
[31] | Gene amplification | 57 | T0–4 | Yes |
[21] | FISH | 62 | T0–4 | NS |
[32] | FISH | 1500 | T0–4 | NS |
[13] | IHC | 55 | T2–4 | NS |
[22] | IHC | 39 | T3-4 | Yes |
[25] | IHC | 109 | T2 | NS |
[33] | IHC | 80 | T2–4 | NS |
[16] | IHC | 184 | T0–4 | NS |
[34] | IHC | 90 | T2–4 | Yes |
[35] | IHC | 138 | T2–4 | Yes |
[36] | IHC | 132 | T2–4 | Yes |
[27] | IHC | 141 | T2–4 | NS |
[37] | IHC | 88 | T0–4 | Yes |
[32] | IHC | 1500 | T0–4 | NS |
[5] | IHC | 245 | T0–4 | Yes |
[23] | IHC | 89 | T0–4 | Yes |
[28] | RT-PCR | 88 | T0–4 | NS |
[29] | RT-PCR | 73 | T0–4 | NS |
| ||||
ErbB3 or ErbB4 | ||||
[16] |
IHC | 128 | T0–4 | NS |
IHC | 124 | T0–4 | Yes |