Table 1.
Copper and iron levels in wild-type and Ctr1+/− mice
| Liver
|
Kidney
|
Spleen
|
Brain
|
|||||
|---|---|---|---|---|---|---|---|---|
| +/+ | +/− | +/+ | +/− | +/+ | +/− | +/+ | +/− | |
| Copper | 6.1 ± 1.0 | 6.3 ± 0.8 | 4.6 ± 0.1 | 4.6 ± 0.3 | 1.0 ± 0.4 | 0.6 ± 0.1* | 3.2 ± 0.1 | 1.7 ± 0.2** |
| Iron | 81.2 ± 10.6 | 67.8 ± 9.0* | 52.1 ± 9.6 | 45.4 ± 6.7 | 175.5 ± 55.9 | 143.1 ± 32.6 | 17.7 ± 1.0 | 15.8 ± 2.4 |
Copper and iron levels (μg/g of tissue) were analyzed for 5- to 6-week-old wild-type (+/+) and Ctr1+/− (+/−) littermates from Ctr1+/− intercrosses. Means of 5–7 mice were compared by Student's t test. *, P < 0.05; **, P < 0.01.