TABLE 1.
Study Group | Inhalation Exposure | Instillation Treatment | Rats/Sacrifice at 48 hr, 96 hr and 7 day Post Instillation |
---|---|---|---|
1 | Ethanol/saline | None - Sham instillations with culture medium | 4 |
2 | Ethanol/saline | Intratracheal instillation of 10,000 influenza particles on exposure day 6 | 8 |
3 | 50 μg/m3 brevetoxin, 2 hr/day for 12 days | None - Sham instillations with culture medium | 4 |
4 | 50 μg/m3 brevetoxin, 2 hr/day for 12 days | Intratracheal instillation of 10,000 influenza particles on exposure day 6 | 8 |