Table 3.
Single SNP association analyses with risk of hypertension.
SNP | Major | Minor | MAF | OR | 95% CI | P value |
---|---|---|---|---|---|---|
rs11571078 | G | A | 0.17 | 1.58 | 1.07, 2.34 | 0.02 |
rs6676670 | C | A | 0.22 | 1.06 | 0.74, 1.51 | 0.75 |
rs6693954 | A | T | 0.32 | 1.98 | 1.40, 2.80 | 0.0001 |
rs10900555 | A | G | 0.40 | 1.33 | 1.00, 1.78 | 0.048 |
rs5705 | A | C | 0.16 | 2.04 | 1.29, 3.21 | 0.002 |
rs1464816 | C | A | 0.33 | 0.91 | 0.66, 1.24 | 0.54 |
Significant associations with hypertension status by logistic regression with adjustment for covariates of age, sex, location and family relatedness are shown (bold font represents significance after Bonferroni correction). P values were obtained for the additive model with minor allele as reference.