Table 2.
Levels of total protein, albumin, low-molecular weight proteins in total and in the four study groups
| All patients | No cART | cART/no TFV | cART/TFV | p-value | TFV/NNRTI | TFV/PI | p-value | ||
|---|---|---|---|---|---|---|---|---|---|
| PCR (mg/g) |
Median (IQR) |
82.8 (56.2, 134.6) |
73.4 (52.5, 111.8) |
84.7 (58.8, 134.2) |
82.7 (56.2, 141.9) |
0.33 |
82.9 (60.9, 141.3) |
82.6 (50.2, 158.0) |
0.88 |
| Log PCR (mg/g) |
Mean (SD) |
4.53 (0.85) |
4.37 (0.66) |
4.58 (0.93) |
4.52 (0.82) |
>0.05 |
4.53 (0.82) |
4.50 (0.83) |
0.82 |
| ACR (mg/g) |
Median (IQR) |
10.3 (5.4, 22.2) |
6.8 (4.9, 15.0) |
11.5 (5.8, 28.9) |
10.0 (5.7, 20.1) |
0.10 |
10.5 (5.7 18.8) |
9.6 (5.5, 24.9) |
0.26 |
| Log ACR (mg/g) |
Mean (SD) |
2.46 (1.16) |
2.19 (1.07) |
2.59 (1.26) |
4.52 (0.82) |
>0.05 |
2.36 (1.08) |
2.48 (1.01) |
0.24 |
| RBPCR (μg/g) |
Median (IQR) |
66.4 (25.5, 150.4) |
61.4 (15.1, 124.6) |
60.4 (24.5, 130.4) |
75.5 (28.2, 169) |
0.24 |
75.23 (27.2, 138.7) |
75.5 (30.6, 241.3) |
0.27 |
| Log RBPCR (μg/g) |
Mean (SD) |
3.92 (1.75) |
3.64 (1.94) |
3.86 (1.69) |
4.13 (1.71) |
>0.05 |
4.02 (1.66) |
4.32 (1.78) |
0.58 |
| NGALCR (ng/g) |
Median (IQR) |
17993 (6998, 44823) |
19658 (7919, 44728) |
20049 (7172, 45319) |
14412 (6011, 43756) |
0.56 |
12770 (5491, 47963) |
17993 (6998, 42732) |
0.44 |
| Log NGALCR (ng/g) |
Mean (SD) |
9.52 (1.99) |
9.39 (2.36) |
9.67 (1.82) |
9.40 (1.99) |
>0.05 |
9.40 (1.90) |
9.40 (2.17) |
0.99 |
| CCR (μg/g) |
Median (IQR) |
2.44 (0.75, 5.39) |
2.70 (0.79, 5.23) |
2.82 (1.01, 5.51) |
1.92 (0.56, 5.10) |
0.13 |
1.92 (0.46, 5.02) |
2.04 (0.70, 5.46) |
0.44 |
| Log CCR (μg/g) | Mean (SD) | 0.80 (1.71) | 0.64 (1.47) | 1.12 (1.82) | 0.50 (1.65) | 0.02 | 0.35 (1.66) | 0.76 (1.63) | 0.29 |
p value for comparison between study groups.
PCR = protein-creatinine ratio (urine); ACR = albumin-creatinine ratio (urine); RBPCR = retinol-binding protein-creatinine ratio (urine); NGALCR = neutrophil gelatinase-associated lipocalin-creatinine ratio (urine); CCR = cystatin C-creatinine ratio (urine).