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. 2012 Jun 22;13:73. doi: 10.1186/1471-2202-13-73

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Copyright ©2012 Lansdell et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Functional expression of Drosophila nAChR subunit combinations in Xenopus oocytes. A) Dose–response curves for acetylcholine are shown for homomeric Dα5 nAChRs (open circles) homomeric Dα7 nAChRs (open squares) and for triplet Dα5 + Dα6 + Dα7 nAChRs (closed circles). B) Dose–response curves for acetylcholine are shown for heteromeric Dα5 + Dα6 nAChRs (open circles) and Dα5 + Dα7 nAChRs (closed circles) In all cases, nAChR subunits were co-expressed with CeRIC-3. Data are means ± SEM of 3–8 independent experiments.