Table 2. Spearman correlation coefficients between marker scores in 146 samples of lung tissue.
| HIF1A (cytoplasm) | MUC1 (membrane) | NKX2-1 (nucleus) | NOTCH1 (cytoplasm) | |||||
| Marker | rS | 95% CI | rS | 95% CI | rS | 95% CI | rS | 95% CI |
| CCND1 (nucleus) | 0.69 | (0.59;0.77) | −0.07 | (−0.23;0.10) | −0.34 | (−0.48; −0.19) | 0.72 | (0.63;0.79) |
| CCND1 (cytoplasm) | 0.73 | (0.64;0.80) | −0.27 | (−0.42; −0.12) | −0.45 | (−0.57; −0.31) | 0.78 | (0.70;0.83) |
| CD44 (membrane) | 0.58 | (0.46;0.68) | −0.08 | (−0.24;0.08) | −0.52 | (−0.63; −0.39) | 0.47 | (0.33;0.59) |
| CD44 (cytoplasm) | 0.56 | (0.43;0.66) | −0.13 | (−0.28;0.04) | −0.45 | (−0.57; −0.31) | 0.48 | (0.34;0.59) |
| CDH1 (membrane) | 0.74 | (0.66;0.81) | −0.15 | (−0.30;0.01) | −0.43 | (−0.55; −0.28) | 0.68 | (0.58;0.76) |
| CDH1 (cytoplasm) | 0.45 | (0.31;0.57) | −0.37 | (−0.50; −0.22) | −0.44 | (−0.56; −0.29) | 0.45 | (0.31;0.57) |
| CTNNB1 (membrane) | 0.79 | (0.72;0.84) | −0.05 | (−0.21;0.11) | −0.40 | (−0.53; −0.25) | 0.74 | (0.65;0.80) |
| CTNNB1 (cytoplasm) | 0.56 | (0.44;0.66) | −0.08 | (−0.24;0.09) | −0.18 | (−0.33; −0.01) | 0.53 | (0.40;0.64) |
| EGFR (membrane) | 0.69 | (0.59;0.77) | −0.08 | (−0.24;0.08) | −0.50 | (−0.61; −0.37) | 0.68 | (0.58;0.76) |
| EGFR (cytoplasm) | 0.68 | (0.58;0.75) | −0.17 | (−0.32;0.00) | −0.46 | (−0.58; −0.32) | 0.70 | (0.61;0.78) |
| ERBB2 (cytoplasm) | 0.58 | (0.46;0.68) | −0.10 | (−0.25;0.07) | −0.30 | (−0.44; −0.14) | 0.68 | (0.58;0.76) |
| HIF1A (cytoplasm) | 1.00 | 0.15 | (−0.02;0.30) | −0.17 | (−0.33; −0.01) | 0.73 | (0.65;0.80) | |
| KIT (cytoplasm) | 0.41 | (0.27;0.54) | −0.30 | (−0.44; −0.14) | −0.25 | (−0.40; −0.10) | 0.47 | (0.33;0.58) |
| KRT14 (membrane) | 0.41 | (0.27;0.54) | 0.01 | (−0.16;0.17) | −0.52 | (−0.63; −0.38) | 0.38 | (0.23;0.51) |
| KRT14 (cytoplasm) | 0.51 | (0.38;0.62) | −0.01 | (−0.17;0.16) | −0.45 | (−0.57; −0.31) | 0.47 | (0.33;0.59) |
| KRT5 (membrane) | 0.51 | (0.38;0.62) | −0.08 | (−0.24;0.08) | −0.61 | (−0.70; −0.49) | 0.47 | (0.33;0.59) |
| KRT5 (cytoplasm) | 0.57 | (0.45;0.67) | −0.06 | (−0.22;0.10) | −0.59 | (−0.68; −0.47) | 0.54 | (0.41;0.64) |
| MMP2 (cytoplasm) | 0.64 | (0.53;0.73) | 0.16 | (0.00;0.31) | −0.07 | (−0.23;0.09) | 0.58 | (0.46;0.68) |
| MUC1 (membrane) | 0.15 | (−0.02;0.30) | 1.00 | 0.58 | (0.46;0.68) | −0.09 | (−0.25;0.08) | |
| MUC1 (cytoplasm) | −0.01 | (−0.17;0.15) | 0.68 | (0.57;0.75) | 0.70 | (0.60;0.77) | −0.13 | (−0.28;0.04) |
| NKX2-1 (nucleus) | −0.17 | (−0.33; −0.01) | 0.58 | (0.46;0.68) | 1.00 | −0.31 | (−0.45; −0.15) | |
| NOTCH1 (cytoplasm) | 0.73 | (0.65;0.80) | −0.09 | (−0.25;0.08) | −0.31 | (−0.45; −0.15) | ||
| PAK1 (nucleus) | 0.36 | (0.20;0.49) | −0.27 | (−0.41; −0.11) | −0.29 | (−0.43; −0.14) | 0.49 | (0.35;0.60) |
| PTGS2 (cytoplasm) | 0.75 | (0.66;0.81) | −0.11 | (−0.27;0.05) | −0.31 | (−0.45; −0.16) | 0.71 | (0.62;0.78) |
| SFTPC (cytoplasm) | 0.84 | (0.78;0.88) | 0.35 | (0.19;0.48) | −0.04 | (−0.20;0.12) | 0.68 | (0.58;0.76) |
| SNAI1 (nucleus) | 0.43 | (0.29;0.55) | −0.41 | (−0.54; −0.26) | −0.38 | (−0.51; −0.23) | 0.45 | (0.31;0.57) |
| SNAI1 (cytoplasm) | 0.33 | (0.18;0.47) | −0.08 | (−0.24;0.08) | −0.16 | (−0.32;0.00) | 0.40 | (0.25;0.52) |
| STAT3 (nucleus) | 0.22 | (0.06;0.37) | 0.11 | (−0.06;0.26) | −0.11 | (−0.27;0.05) | 0.09 | (−0.07;0.25) |
| STAT3 (cytoplasm) | 0.64 | (0.53;0.72) | 0.17 | (0.00;0.32) | −0.02 | (−0.18;0.14) | 0.55 | (0.42;0.65) |
| TP53 (nucleus) | 0.34 | (0.18;0.47) | −0.30 | (−0.44; −0.14) | −0.34 | (−0.48; −0.19) | 0.37 | (0.22;0.50) |
| TP53 (cytoplasm) | 0.30 | (0.14;0.44) | −0.10 | (−0.25;0.07) | −0.03 | (−0.19;0.13) | 0.24 | (0.08;0.38) |
| VEGFA (cytoplasm) | 0.55 | (0.42;0.65) | −0.38 | (−0.51; −0.23) | −0.33 | (−0.47; −0.18) | 0.55 | (0.42;0.65) |
| VIM (membrane) | 0.38 | (0.23;0.51) | 0.01 | (−0.15;0.18) | −0.20 | (−0.35; −0.04) | 0.31 | (0.15;0.45) |
| VIM (cytoplasm) | 0.34 | (0.18;0.47) | 0.02 | (−0.14;0.19) | −0.08 | (−0.24;0.09) | 0.36 | (0.21;0.49) |