Table 4. Top 20 tissue-specific pathways with highest degrees.

Tissue	Pathway	Description	Degree
Liver	mmu00010	Glycolysis/Gluconeogenesis	82
Liver	mmu00020	Citrate cycle (TCA cycle)	55
Liver	mmu00252	Alanine and aspartate metabolism	46
Liver	mmu00620	Pyruvate metabolism	45
Adipose	mmu00010	Glycolysis/Gluconeogenesis	40
Liver	mmu00260	Glycine, serine and threonine metabolism	37
Islet	mmu00620	Pyruvate metabolism	37
Liver	mmu00030	Pentose phosphate pathway	34
Islet	mmu00230	Purine metabolism	33
Islet	mmu00630	Glyoxylate and dicarboxylate metabolism	32
Islet	mmu00010	Glycolysis/Gluconeogenesis	30
Liver	mmu00630	Glyoxylate and dicarboxylate metabolism	29
Liver	mmu00280	Valine, leucine and isoleucine degradation	26
Hypothalamus	mmu00040	Pentose and glucuronate interconversions	26
Adipose	mmu00400	Phenylalanine, tyrosine and tryptophan biosynthesis	26
Adipose	mmu00230	Purine metabolism	25
Adipose	mmu04010	MAPK signaling pathway	25
Liver	mmu00040	Pentose and glucuronate interconversions	24
Liver	mmu00251	Glutamate metabolism	24
Liver	mmu00220	Urea cycle and metabolism of amino groups	24