Table 8. Pathways with the most significant interactions in the BTBR obese 10 week mice.

Tissue	Pathway	Name	Network degree	p-value	FDR
Hypothalamus	mmu00190	Oxidative phosphorylation	27	8.5E-07	0.00063
Islet	mmu04660	T cell receptor signaling pathway	58	1.1E-05	0.0080
Soleus	mmu05332	Graft-versus-host disease	35	0.00045	0.331
Adipose	mmu05332	Graft-versus-host disease	35	0.00045	0.331
Adipose	mmu05320	Autoimmune thyroid disease	31	0.00065	0.477
Gastrocnemius	mmu00190	Oxidative phosphorylation	20	0.00072	0.532
Adipose	mmu04510	Focal adhesion	20	0.00072	0.532
Adipose	mmu04940	Type I diabetes mellitus	16	0.00076	0.556
Hypothalamus	mmu05012	Parkinsons disease	30	0.0012	0.911
Adipose	mmu05330	Allograft rejection	30	0.0012	0.912
Adipose	mmu05012	Parkinsons disease	30	0.0012	0.912
Gastrocnemius	mmu00760	Nicotinate and nicotinamide metabolism	23	0.0013	0.934
Gastrocnemius	mmu04514	Cell adhesion molecules (CAMs)	43	0.0013	0.978