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. 2012 Sep 17;7(9):e45102. doi: 10.1371/journal.pone.0045102

Figure 3. DCs loaded with CD11c-scFv-IDRgag induced proliferation of FV-specific CD8+ T cells.

Figure 3

(A) To study proliferation of FV-specific CD8+ T cells induced by CD11c-scFv-IDRgag treated bmDCs, isolated FV-specific TCRtg CD8+ T cells were stained with CFSE prior to co-culture with bmDCs. After 4 days of co-culture both control-scFv-IDRgag and CD11c-scFv-gagID-loaded bmDCs induced proliferation of FV-specific CD8+ T cells. (B) The proliferation of CD8+ T cells induced by CD11c-scFv-IDRgag was significantly higher compared to DCs with control-scFv-IDRgag. Data represent mean±SD of 5 independent experiments. Data were analyzed with unpaired t-test.