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| NMDA concentration (mM) | n | Decrease in MAP (mmHg) | Increase in HR (bpm) |
| 2.5 | 4 | 5.3±1.4‡ | 8.5±0.6† |
| 5 | 4 | 10.3±1.7** | 22.3±5.1 |
| 10 | 4 | 11.8±1.7** | 25.0±7.2* |
ARCN: the hypothalamic arcuate nucleus; bpm: beats/min; HR: heart rate; MAP: mean arterial pressure; NMDA: N-methyl-D-aspartic acid. **Significantly greater compared with ‘‡’ (P<0.01). *Significantly greater compared with ‘†’ (P<0.05). The volume of all microinjections was 20 nl.
