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Effect of MSC on CD4+ T cell differentiation toward (A) the Th1 or (C) Th17 lineages (CD4-Th1 or CD4-Th17, respectively) or on mature (B) Th1 or (D) Th17 cells when cultured in absence of a physical contact between the cells using a transwell system (MSC:T cell ratio of 1∶10). P values referred to the condition without MSC (no MSC).
