Table 6. Clinical performances of the molecules for discriminating tPA treated (N = 12) vs. ineligible patients (N = 104).

		High Se			High Sp
Molecules	AUC	CO	Se/Sp	OR	CO	Se/Sp	OR
	(95%CI)	(units)	(%)		(units)	(%)
GST-π	0.83*	17.7	91.7/45.6	9.3	65.2	58.3/89.3	11.7
	(0.71–0.95)
NDKA	0.69	4.4	91.7/40.8	8.6	23.1	16.7/89.3	1.7
	(0.57–0.82)
DJ-1	0.62	50.8	91.7/37.3	6.6	443.0	8.3/95.1	1.7
	(0.48–0.75)

^*The AUC of GST-π was significantly better than AUC of DJ-1 (p = 0.016). No significant difference was obtained between GST-π vs. NDKA (p = 0.11) and NDKA vs. DJ-1 (p = 0.14).

An AUC above 0.80 was estimated as significant (significance 0.05 and power 0.95, made with Power tests/Sample size item from pROC software).