Table 1.

Polymorphisms in FcγRIIB gene and response to IVIG treatment among Kawasaki disease patients in all ethnic groups and only Caucasians

Polymorphisms	Minor Allele Freq (%)			Allelic Odds Ratios (95% CI) Rp vs. NRp	p-value
	Parents	Responders (Rp)	Non-Responders (NRp)		Allelica	Genotypeb	Trendc
All Ethnic groups	n = 578	n=231	n=76
FcγRIIB+775T/c	15	18	14	1.35 (0.0.79-2.22)	0.28	0.42	0.34
FcγRIIB -386G/c	9	10	7	1.61 (0.79-3.23)	0.18	0.32	0.12
FcγRIIB -120T/a	9	10	5	2.22 (0.98-5.02)	0.05	0.17	0.06
Caucasians	n = 369	n=129	n=48
FcγRIIB+775T/c	13	12	13	0.97 (0.47-2.01)	0.94	0.97	0.95
FcγRIIB −386G/c	13	16	8	2.04 (0.91-4.55)	0.08	0.21	0.10
FcγRIIB −120T/a	12	15	5	3.23 (1.22-8.33)	0.01	0.03	0.02
Asians	n = 86	n=40	n=8
FcγRIIB+775T/c	27	40	19	1.54 (0.39-6.25)	0.11	0.15	0.14
FcγRIIB −386G/c	1	0	0	-	-	-	-
FcγRIIB -120T/a	0	0	0	-	-	-	-
Hispanic	n =67	n=29	n=11
FcγRIIB+775T/c	11	20	14	-	0.49	0.65	0.51
FcγRIIB −386G/c	3	4	0	-	-	-	-
FcγRIIB -120T/a	4	3	0	-	-	-	-

^aχ² (d.f.=1);

^bχ² (d.f.=2);

^cCochran-Armitage test