Table 2.
Susceptibility of Plasmodium vivax in the Republic of Korea to antimalarial drugs using the schizont maturation inhibition assay compared with results from Thailand*
| Drug | Geometric mean IC50 (ng/mL) (95% CI) |
|
|---|---|---|
| Isolates from Thailand15 (n = 50) |
Isolates from the Republic of Korea (n = 24) |
|
| Quinine | 308 | 59 (54–75) |
| Chloroquine | 50 | 39 (22–282) |
| Mefloquine | 127 | 39 (35–67) |
| Pyrimethamine | 8 | 137 (89–280) |
| Artesunate | 0.5 | 0.58 (0.5–0.8) |
| Primaquine | ND | 121 (98–232) |
| Piperaquine | ND | 27 (17–-58) |
*
Data are the mean of geometric 50% inhibition concentration (IC50) and 95% confidence interval (CI). ND = no data.