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. Author manuscript; available in PMC: 2013 Nov 1.
Published in final edited form as: Biomaterials. 2012 Aug 19;33(33):8265–8276. doi: 10.1016/j.biomaterials.2012.07.041

Fig. 5. Parameter sensitivity analysis of the intracellular pathway model.

Fig. 5

Above subfigure shows that the expression of Runx2 is more sensitivity to V6, K6 and d4. Below subfigure shows that the expression of Osx is more sensitivity to V8, K8 and d8, as well as to V1, K1, d1 and V7, K7. These results show us which kinetic parameters and molecules are more important in the system and also demonstrate that the developed intracellular pathway system is robust.