Table 4.

Average annual wholesale costs for medical foods with protein in 2010 for select newborn screened disorders supplying Dietary Reference Intake age-based protein requirements [8].

Estimated Average Costs ($) for Age-Based Protein Requirements per Year for Select Disorders Screened in the Newborn Perioda
Age in years	DRI protein requirements in grams (g)	PKU	PA	MMA	HCY	MSD	GA 1	Tyr-1	IVA	Average
Less than 1	10	1,248	1,900	1,900	1,747	1,766	1,970	1,963	2,074	1,817
1–3	13	1,806	2,745	2,745	2,524	2,551	2,845	2,836	2,991	2,520
4–8	19	2,643	3,494	3,494	3,689	3,728	3,054	3,730	3,817	3,456
9–13	34	4,829	6,252	6,252	5,816	6,185	6,488	7,111	7,060	6,249
Males 14–18	52	7,386	9,537	9,537	8,895	9,459	9,922	10,876	10,798	9,551
Females 14 to older than 70	46	6,534	8,436	8,436	8,513	8,368	8,777	9,621	9,552	8,530
Males 19 to older than 70 and pregnant females	60	8,522	11,004	11,004	10,264	10,915	11,449	12,549	12,459	11,021

DRI = Dietary Reference Intake; PKU = phenylketonuria; PA = propionic academia; MMA = methylmalonic academia; HCY = homocystinuria; MSD = maple syrup disease; GA1 = glutaric aciduria, type 1; Tyr-1 = tyrosinemia, type 1; IVA = isovaleric academia

^aThe average cost for the medical foods with protein is based on the individual wholesale cost of a selection of products manufactured to treat each disorder. The cost associated with the amount of product providing a specific amount of protein was determined for each product and then averaged across all products.