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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Mol Genet Metab. 2012 Jul 14;107(1-2):161–172. doi: 10.1016/j.ymgme.2012.07.002

Figure 7.

Figure 7

Histopathology of wild-type (36 weeks old), untreated MPS VII (32 weeks old), and IP PerT-GUS treated MPS VII mice (27 weeks old). Images are of the growth plate, articular cartilage, trabecular bone/bone marrow, and cortical bone. Tissue was stained with toluidine blue. Arrows on growth plate and articular cartilage micrographs identify distended chondrocytes. Arrows on cortical bone micrographs identify distended osteocytes, which are more prevalent in untreated MPS VII bone than in PerT-GUS treated MPS VII bone. GP: growth plate, BM: bone marrow, M: meniscus, AC: articular cartilage.