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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Mol Genet Metab. 2012 Jul 14;107(1-2):161–172. doi: 10.1016/j.ymgme.2012.07.002

Figure 8.

Figure 8

Quantitative analysis of histopathology of tibias in wild-type (n = 5), untreated MPS VII (n = 4), and IP PerT-GUS treated MPS VII mice (n = 5). (A) Shows growth plate and articular cartilage thickness. (B) Number of chondrocytes in a given area of the articular cartilage (cellularity). (C) Number of chondrocytes in a given area of the proliferative zone of the growth plate (cellularity). (D) Cross sectional cell area of chondrocytes in the proliferative zone of the growth plate or articular cartilage, values reported are means of measurements taken for all chondrocytes in one 40X microscope field. (E) Number of cells in each proliferative zone column in the growth plate. Values reported are means of the number of cells in each column in one 40X microscope field. (F) Perimeter to length ratio measured as shown in Supplemental Fig. 4. * represents p < 0.05. Error bars represent one standard deviation.