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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Am J Surg Pathol. 2012 Oct;36(10):1452–1463. doi: 10.1097/PAS.0b013e31825d538b

Table 3.

Treatment, Gross Pathologic Findings, And Initial Pathologic Diagnoses For 3 Neonates With Bilateral Adrenal Enlargement And Hypercortisolemia

Adrenal Weight, g
Case Surgical Treatment Age at Adrenalectomy, mo Right Left Gross Appearance Initial Pathologic Diagnosis
1 Left adrenalectomy and excision of ectopic left adrenal cytomegalic masses (up to 4 × 2.5 × 2 cm) 1 Not resected; gland enlarged 52 Bulging dark brown nodules, externally. Cut surface showed brown lobules limited by a narrow yellow periphery Multinodular adrenal with cytomegalic changes
2 Bilateral adrenalectomy 2 28.7 15.4 Gyriform appearance with yellow and dark blue areas, externally. Cut surface showed flesh-colored, irregularly shaped lobules, many with a brownish center Fetal adrenal hyperplasia and adult cortex
3 Bilateral adrenalectomy 3 30.1 22.5 Cerebriform appearance with gray and yellow nodules, externally. Cut surface featured lobules with yellow periphery and central dark red core. Three 0.5-cm pseudocysts Diffuse adrenocortical hyperplasia with cytomegaly