FIG. 4.

Hyaluronidase (HAase) treatment worsens the tail swelling. Control tissue (A) was compared to mouse tails that received HAase in low (B), medium (C), and high doses (D). Images show tails at days 12 (left) and 24 (right), with distal direction at the top and proximal direction at the bottom of each image. Peak swelling diameters for each tail are graphically depicted in E. Scale bar (D, bottom, right)=5 mm, n=7 mice for the low and high dose groups, and n=6 mice for the control and medium dose groups.