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. Author manuscript; available in PMC: 2013 Sep 15.
Published in final edited form as: Bioorg Med Chem Lett. 2012 Jul 15;22(18):5999–6003. doi: 10.1016/j.bmcl.2012.06.097

Scheme 2.

Scheme 2

Synthesis of 4-styryl-3,5-bis(4-hydroxyphenyl) isoxazoles 4a–4m via the 4-iodo intermediate and commercially available styryl/alkylvinyl boronic acids.