Figure 3.

Distribution of mutations found in the VP1 capsid gene without ribavirin (Δ), with 400 μM ribavirin mutagenesis (*), and 1,000 μM ribavirin mutagenesis (♦). Note that there are no particular mutational hotspots. Almost all mutations at Cs were C→U and mutations at Gs were G→A. Also note that in the presence of 400 μM ribavirin an unusual 3 nt deletion (indicated by —) was detected at a CCA sequence.