Table 7.
ALP (IU/mg protein/ml × 10−2) | GGT (IU/mg protein/ml × 10−2) | |||
---|---|---|---|---|
Groups | 12 h | 24 h | 12 h | 24 h |
CONTROL | 0.829 ± 0.04 | 0.605 ± 0.05 | 0.0159 ± 0.0007 | 0.013 ± 0.0006 |
CYP-0.06 mg/kg bw | 0.903 ± 0.04a | 0.714 ± 0.04b | 0.0213 ± 0.0006a,d | 0.0184 ± 0.0005a,d |
CYP-0.12 mg/kg bw | 0.511 ± 0.04e,d | 0.803 ± 0.04b,d | 0.0162 ± 0.0006 | 0.0154 ± 0.0004d |
CYP-0.30 mg/kg bw | 0.858 ± 0.04 | 0.768 ± 0.04b,d | 0.0146 ± 0.0006 | 0.014 ± 0.0007a |
CYP-0.60 mg/kg bw | 0.828 ± 0.07 | 0.744 ± 0.05b,a | 0.0182 ± 0.0007d | 0.017 ± 0.0009a,d |
CAR-0.48 mg/kg bw | 0.561 ± 0.03d | 0.597 ± 0.03a | 0.0167 ± 0.0005 | 0.010 ± 0.0005a,d |
CAR-0.96 mg/kg bw | 0.600 ± 0.03b,d | 0.660 ± 0.04b | 0.024 ± 0.0005a,d | 0.011 ± 0.0007a,d |
CAR-2.4 mg/kg bw | 0.609 ± 0.04b,d | 0.680 ± 0.05a | 0.0173 ± 0.0006 | 0.014 ± 0.0007a |
CAR-4.8 mg/kg bw | 0.792 ± 0.04b | 0.770 ± 0.05b,d | 0.0191 ± 0.0008d | 0.0089 ± 0.0006b,d |
CYP-0.06 + CAR-0.48 mg/kg bw | 0.793 ± 0.04a | 0.686 ± 0.04b | 0.0157 ± 0.0004 | 0.0202 ± 0.0010a,d |
CYP-0.12 + CAR-0.96 mg/kg bw | 0.692 ± 0.03b,d | 0.703 ± 0.06b | 0.0165 ± 0.0006 | 0.0222 ± 0.0007a,d |
CYP-0.30 + CAR-2.4 mg/kg bw | 0.689 ± 0.04b,d | 0.695 ± 0.04a | 0.0232 ± 0.0009a,d | 0.0198 ± 0.0008a,d |
CYP-0.60 + CAR-4.8 mg/kg bw | 0.769 ± 0.04a | 0.660 ± 0.07a | 0.0152 ± 0.0004 | 0.0158 ± 0.0005d |
Values are mean ± SEM from 6 rats in each group.
P < 0.05,
P < 0.01 and
P < 0.001: Compared between the control and treated groups.
P < 0.05 and
P < 0.01: Compared between the treated groups. Data analysed by one-way anova followed by Dunnett test.