FIG. 2.

Schematic diagram of the chromosomal domain in M. tuberculosis. The IS6110 insertion elements are depicted by bold black arrows where the orientation is 3′ (tail) to 5′ (head). IS6110 insertions for which the orientation is unknown are depicted by bold black lines. The respective insertion points are indicted by vertical numbers, which relate to the whole genome sequence of H37Rv (3). Each insertion locus is numbered according to the numbering in reference 12. Open reading frames, according to the annotation of the whole genome sequences of H37Rv (3) and CDC1551 (7), are indicated by the grey arrows. Dotted lines indicate chromosomal deletions. Deletion RvD2 was assigned as described in reference 8. Thin arrows indicate the primer positions, while the hatched lines indicate regions sequenced.