Table 3.

Homologies between Cup components and components of known chaperone/usher pathways

Gene name	PA number*	Protein size, aa†	Predicted function	Nearest homolog‡	Identity, %/residues§
cupA1	2128	183	Fimbrial subunit	F17A/E. coli	37/28–160
cupA2	2129	248	Chaperone	F17a–D/E. coli	35/28–239
cupA3	2130	872	Usher	FocD/E. coli	40/25–861
cupA4	2131	454	Fimbrial subunit		29/19–230
cupA5	2132	237	Chaperone	FhaD/B. pertussis	34/17–225
cupB1	4086	189	Fimbrial subunit	F17A/E. coli	33/16–180
cupB2	4085	248	Chaperone	FhaD/B. pertussis	37/13–246
cupB3	4084	844	Usher	F17a–C/E. coli	32/19–817
cupB4	4083	246	Chaperone	FhaD/B. pertussis	41/31–235
cupB5	4082	1018	Adhesive protein	HxuA/H. influenzae	34/55–398
cupB6	4081	381	Fimbrial subunit	LpfE/S. typhimurium	25/245–380
cupC1	0992	205	Fimbrial subunit	Type 1/K. pneumoniae	28/26–152
cupC2	0993	237	Chaperone	EcpD/E. coli	37/16–227
cupC3	0994	839	Usher	FimD/E. coli	34/3–775

^*The PA number corresponds to the genome annotation (http://www.pseudomonas.com). 

^† The protein size is indicated in number of amino acids (aa). 

^‡ For CupA4 see text. HxuA is the heme–hemopexin utilization protein from Haemophilus influenzae. CupB5 is also highly homologous to HMW1 (28% identity), the high molecular weight surface protein from H. influenzae and Fha, the filamentous hemagglutinin from Bordetella pertussis (23% identity). S., Salmonella; K, Klebsiella. 

^§ The percentage identity is assigned to the region of the protein including the indicated amino acid residues.