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. 2001 May 29;98(12):6917–6922. doi: 10.1073/pnas.111134598

Figure 3.

Figure 3

Effect of COMT genotype on fMRI activation during the two-back working memory task in a second group of subjects. Again, Val/Val individuals showed greater activation (and by inference greater inefficiency) than Val/Met individuals who showed less efficiency than Met/Met individuals in the dorsal prefrontal cortex and several other locales.