Table 3:
Prognostic factors: histomorphological
| Histological growth patterns | Number of patients | Five-year survival (%) | Median survival (months) | P-value |
|---|---|---|---|---|
| Mitoses/10 HPF (mitotic index) | ||||
| 1–9 | 12 | 60.8 | n.p. | |
| 10–19 | 16 | 42.9 | 40 | *0.125 |
| >19 | 24 | 40.4 | 31 | *0.066 |
| Presence of a pseudocapsule | ||||
| Yes | 11 | 63.6 | n.p. | |
| No | 41 | 39.6 | 42 | 0.198 |
| Resection margins | ||||
| R0 | 36 | 59.8 | 71 | |
| R1 | 16 | 10.9 | 25 | 0.017 |
| Pleural penetration | ||||
| No | 34 | 50.9 | 63 | |
| Yes | 18 | 32.4 | 38 | 0.330 |
| Vascular infiltration | ||||
| No | 29 | 54.6 | 63 | |
| Yes | 23 | 33.1 | 35 | 0.070 |
| Interstitial growth | ||||
| No | 26 | 64.6 | n.p. | |
| Yes | 26 | 27.8 | 34 | 0.008 |
| Tumour satellites | ||||
| No | 33 | 40.5 | 71 | |
| Yes | 19 | 50.7 | 43 | 0.707 |
| Lymphangitic spread | ||||
| No | 44 | 43.5 | 50 | |
| Yes | 8 | 50 | 40 | 0.701 |
| Signs of tumour regression | ||||
| No | 33 | 52.8 | 63 | |
| Yes | 19 | 18.9 | 35 | 0.272 |
n.p.: Not possible; HPF: high-power fields.
*Probabilities are calculated vs (1–9).