Table 1:
Patient variables | IL-6 <500 pg/mla | IL-6 between 500 and 1500 pg/mla | IL-6 >1500 pg/mla | All |
---|---|---|---|---|
Number of patients | 6 | 6 | 7 | 19 |
Age (years) at transplant: mean (SD) | 46.5 (±13.6) | 51.3 (±14.7) | 38.1 (±17.6) | 44.9 (±16) |
Sex, male: n (%) | 4 (67%) | 5 (83%) | 3 (43%) | 12 (63%) |
Preoperative diagnosis | ||||
Obstructive disease | 3 (50%) | 2 (33%) | 2 (29%) | 7 (37%) |
Restrictive disease | 1 (17%) | 2 (33%) | 1 (14%) | 4 (21%) |
Cystic fibrosis | 3 (50%) | 1 (17%) | 0 (0%) | 4 (21%) |
Pulmonary hypertension | 0 (0%) | 0 (0%) | 3 (43%) | 3 (16%) |
Re-transplantation? (%) | 4 (67%) | 0 (0%) | 2 (29%) | 6 (32%) |
Bilateral transplantation: n (%) | 1 (17%) | 1 (17%) | 4 (57%) | 6 (32%) |
Ischaemic time (min): mean (SD)b | 253.7 (±57.5) | 221.7 (±100.8) | 301.4 (98.1) | 265.3 (±82.1) |
Cardiopulmonary bypass: n (%) | 2 (33%) | 0 (0%) | 4 (57%) | 6 (32%) |
Perioperative blood transfusions: n (%) | 2 (33%) | 0 (0%) | 1 (14%) | 3 (16%) |
Postoperative pneumonia: n (%) | 3 (50%) | 2 (33%) | 2 (29%) | 7 (37%) |
Postoperative CMV infection: n (%) | 2 (33%) | 2 (33%) | 3 (43%) | 7 (37%) |
PaO2/FiO2 ratio: mean, (SD)c | 334 (±45.8) | 346 (±212) | 222 (±99.4) | 297 (±141) |
Average PGD Grade (SD) | 0.67 (±0.81) | 1.33 (±1.36) | 2.28 (±0.75) | 1.47 (±1.17) |
pg: picograms; ml: millilitres; n: number; SD: standard deviation; PaO2: systemic arterial oxygen pressure; FiO2: inspired fraction of oxygen; PGD: primary graft dysfunction; CMV: cytomegalovirus.
aIL-6 levels at t = 4 h post-transplantation surgery were used.
bIn the case of bilateral transplant, the higher ischemic time of the two was used.
cWorst PaO2/FiO2 in the 72 h following transplant was used.