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. 2012 Jul 19;15(4):603–607. doi: 10.1093/icvts/ivs330

Table 1:

Demographic variables and short-term outcomes of patients separated based on IL-6 response

Patient variables IL-6 <500 pg/mla IL-6 between 500 and 1500 pg/mla IL-6 >1500 pg/mla All
Number of patients 6 6 7 19
Age (years) at transplant: mean (SD) 46.5 (±13.6) 51.3 (±14.7) 38.1 (±17.6) 44.9 (±16)
Sex, male: n (%) 4 (67%) 5 (83%) 3 (43%) 12 (63%)
Preoperative diagnosis
 Obstructive disease 3 (50%) 2 (33%) 2 (29%) 7 (37%)
 Restrictive disease 1 (17%) 2 (33%) 1 (14%) 4 (21%)
 Cystic fibrosis 3 (50%) 1 (17%) 0 (0%) 4 (21%)
 Pulmonary hypertension 0 (0%) 0 (0%) 3 (43%) 3 (16%)
 Re-transplantation? (%) 4 (67%) 0 (0%) 2 (29%) 6 (32%)
Bilateral transplantation: n (%) 1 (17%) 1 (17%) 4 (57%) 6 (32%)
Ischaemic time (min): mean (SD)b 253.7 (±57.5) 221.7 (±100.8) 301.4 (98.1) 265.3 (±82.1)
Cardiopulmonary bypass: n (%) 2 (33%) 0 (0%) 4 (57%) 6 (32%)
Perioperative blood transfusions: n (%) 2 (33%) 0 (0%) 1 (14%) 3 (16%)
Postoperative pneumonia: n (%) 3 (50%) 2 (33%) 2 (29%) 7 (37%)
Postoperative CMV infection: n (%) 2 (33%) 2 (33%) 3 (43%) 7 (37%)
PaO2/FiO2 ratio: mean, (SD)c 334 (±45.8) 346 (±212) 222 (±99.4) 297 (±141)
Average PGD Grade (SD) 0.67 (±0.81) 1.33 (±1.36) 2.28 (±0.75) 1.47 (±1.17)

pg: picograms; ml: millilitres; n: number; SD: standard deviation; PaO2: systemic arterial oxygen pressure; FiO2: inspired fraction of oxygen; PGD: primary graft dysfunction; CMV: cytomegalovirus.

aIL-6 levels at t = 4 h post-transplantation surgery were used.

bIn the case of bilateral transplant, the higher ischemic time of the two was used.

cWorst PaO2/FiO2 in the 72 h following transplant was used.