Figure 3. Protective effects of nLDL immunization in euglycemic female mice fed regular chow.

To assess direct effects of immunization on glucose responses, OGTTs were performed on separate groups of female mice 40 and 250 days after the primary immunization. Controls were non-immunized. (A) Body weights at both time points. (B) Glucose responses after 40 days. (C,D) Glucose and insulin responses after 250 days. AUC, Area under the curve. n = 24 (40 days) and 25 (250 days).