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. 2012 Sep 18;7(9):e45260. doi: 10.1371/journal.pone.0045260

Figure 2. Specific activation of NOD1 promotes cardiac dysfunction.

Figure 2

(A) Ejection fraction obtained in mice treated for 2 weeks (daily) with vehicle or the indicated concentrations of iE. (B) Ejection fraction obtained in mice treated during 3, 7 or 14 days with vehicle or 150 µg of iE. (C,D) Representative echocardiographic images (M mode) of mouse hearts treated for two weeks with vehicle (C) or 150 µg of iE (D). End Systolic Diameter (ESD), End Diastolic Diameter (EDD), and left ventricle Posterior Walls (PW) are indicated. *p<0.05, ***p<0.001 vs. vehicle.