Figure 1. Cultured IFN-γ ELISpot responses to causal drugs.

PBMCs from patients with SJS and TEN or MPE were incubated with either causal drugs or irrelevant drugs for 10 days. The cells were subsequently washed, and then stimulated with causal drugs or irrelevant drugs in an IFN-γ ELISpot assay. Responses are presented as number of IFN-γ-positive spot-forming units (SFU) per million cells. Each data point represents an individual patient with SJS and TEN or MPE. Median is indicated by a horizontal line. *P<0.01.