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. 2012 Sep 18;7(9):e45494. doi: 10.1371/journal.pone.0045494

Table 1. Functional categories overrepresented in the microarray data.

Category p-value In Category from Cluster
Down-regulated genes
MIPS Functional Classification
rRNA processing 1.9E−7 40 GENES
MIPS Subcellular Localization
nucleolus 3.5E−6 50 GENES
MIPS Protein Complexes
RNA polymerase II 8.7E−6 RPB4, RPB5, RPB8, RPB9, RPB10, RPB11, RPC10, RPO26
PFam-A Domains
LSM 1.1E−12 LSM2, LSM3, LSM4, LSM5, LSM6, LSM7, LSM8, MAK31, SMB1, SMD1, SMD2, SMD3, SME1, SMX2
Up-regulated genes
MIPS Functional Classification
Glycolysis and gluconeogenesis 8.3E−7 CDC19, ENO1, GLK1, LAT1, PDA1, PGM2, PYC1, PYC2, PYK2, ZWF1
Metabolism of energy reserves (e.g. glycogen, trehalose) 2.4E−6 FKS1, GDB1, GPH1, GSY2, KRE5, NTH1, PGM2, TPS1, TPS2, TPS3, TSL1
MIPS Phenotypes
Starvation sensitivity 1.9E−5 BCY1, IRA2, KEM1, PEP4, RVS167, SRV2, VRP1
MIPS Subcellular Localization
Transport vesicles 8.8E−5 APM1, COP1, RPG1, SEC7, SEC16, SEC18, SEC21, SEC24
Plasma membrane 1.9E−4 CSF1, CYR1, DNF1, FKS1, FUI1, GAP1, HXT2, IRA1, IRA2, IST2, KIN1, RSP5, SEC3, SED1, SSO2, YPS1, YPS3
GO Biological Process
Vacuolar protein catabolic process 2.6E−8 AIM3, ATG2, APE3, CAR2, CSF1, CWP1, GAP1, HPF1, IRA1, IST2, LAT1, NCR1, PDA1, PEP4, PRB1, PYC1, VPS13, VRP1, YIL169C
Endocytosis 2.7E−7 CHC1, DNF1, EDE1, FKS1, INP53, MYO5, NEO1, PAN1, PIL1, RSP5, RVS167, SDS24, SLA1, SVL3SWH1, VRP1
GO Cellular Component
Actin cortical patch 3.9E−6 ABP1, BBC1, EDE1, FKS1, INP53, MYO5, PAN1, RVS167, SRV2, VRP1,