Table 2. Association between rs3802842 and colorectal cancer risk in a Chinese populationa.
| Case | Control | OR (95% CI) | ||||||
| AA/AC/CC | AA/AC/CC | C VS. A | AC VS. AA | CC VS. AA | Dominant model | Recessive model | Additive model | |
| Total | 163/345/133 | 397/477/163 | 1.44 (1.25–1.66) | 1.76 (1.40–2.21) | 1.99 (1.48–2.67) | 1.82 (1.46–2.26) | 1.41 (1.09–1.82) | 1.45 (1.26–1.67) |
| Tumor site | ||||||||
| Colon | 52/148/50 | 397/477/163 | 1.56 (1.28–1.89) | 2.37 (1.68–3.34) | 2.34 (1.52–3.59) | 2.36 (1.70–3.28) | 1.34 (0.94–1.91)b | 1.57 (1.28–1.91) |
| Rectum | 111/197/83 | 397/477/163 | 1.38 (1.17–1.63) | 1.47 (1.12–1.92) | 1.85 (1.32–2.59) | 1.57 (1.22–2.02) | 1.47 (1.09–1.98)b | 1.37 (1.16–1.62) |
| Tumor differentiation | ||||||||
| Poorly+Moderately | 137/280/108 | 397/477/163 | 1.42 (1.22–1.65) | 1.70 (1.33–2.17) | 1.92 (1.41–2.63) | 1.76 (1.39–2.21) | 1.39 (1.06–1.82)b | 1.42 (1.22–1.65) |
| Well | 26/65/25 | 397/477/163 | 1.56 (1.18–2.05) | 2.03 (1.26–3.26) | 2.39 (1.33–4.27) | 2.12 (1.34–3.34) | 1.53 (0.95–2.46)b | 1.56 (1.18–2.05) |
Abbreviations: OR, Odds ratio; 95% CI, 95% confidence interval.
a
ORs and their corresponding 95% CIs were calculated by multivariate logistic regression model after adjusting for age and sex.
b
The association between rs3802842 and colorectal cancer risk turned to be null significant after Bonferroni correction for multiple testing was applied.