Table 3. The Most Overrepresented Pathways for miR-150 targets According to KEGG*.
KEGG Pathway Term | Count | P value | GENE NAMES | |
hsa04150:mTOR signaling pathway | 2 | 0.0218 | EIF4E, EIF4B | |
Inflammation system | hsa04010: MAPK signalingpathway | 4 | 0.0136 | ARRB2, MAPK9, MAP2K4, PAK1 |
hsa04910:Insulin signaling pathway | 2 | 0.0347 | PRKAR1A, EIF4E | |
hsa04350:TGF-beta signaling pathway | 1 | 0.0379 | SP1 | |
hsa04012:ErbB signaling pathway | 1 | 0.0391 | CAMK2G | |
hsa04310:Wnt signaling pathway | 1 | 0.046 | PRKCA | |
Apoptosis | hsa04210:Apoptosis | 2 | 0.0215 | IRAK2, PRKAR1A |
1 | 4.16E-03 | CAST | ||
calcium ion channels | 1 | 1.24E-02 | CAMK2G | |
1 | 3.68E-02 | KCNIP1 | ||
1 | 0.0389 | KCNIP1 | ||
fibrosis | 1 | 0.0392 | TPM3 |
Count, number of potential target genes in the pathway. The gene name is presented as in NCBI at http://www.ncbi.nlm.nih.gov.