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. 2012 Sep 18;7(9):e44993. doi: 10.1371/journal.pone.0044993

Figure 5. Relationships among annual changes in CT parameters of emphysema.

Figure 5

A and B show relationships between the changes in LAA% and D and between those in LAA% and LAN, respectively, in 22 current and 31 former smokers with mild to moderate emphysema. Closed and open circles, current and former smokers, respectively. Solid and dashed regression lines, current and former smokers, respectively. Changes in LAA% in current and former smokers significantly correlated with those in D (r = −0.77, p<0.0001; r = −0.53, p = 0.002, respectively) and LAN (r = 0.88, p<0.0001 and r = 0.90, p<0.0001, respectively). Smoking status and change in LAA% significantly interacted to elicit changes in D (p = 0.03), but not in LAN (p = 0.48).