Table 6. Caspase activity of C. albicans cells after AMB treatment6.
Strains | 2 μg/ml AMB |
HSP90/HSP90 | 50.72±0.49 |
tetO-HSP90/hsp90 | 32.22±0.45* |
HSP90/HSP90+DOX | 51.92±2.34 |
tetO-HSP90/hsp90+DOX | 22.83±0.46* |
After treatment with or without 20 μg/ml DOX for 3 h, caspase activity of C. albicans cells was detected flow cytometry after D2R staining. Three independent experiments were carried out and the results were presented as the mean ± SD of D2R positive cells percentage. * indicated p<0.05 compared with the wild-type strain group.