Table 1.
Affinity constants for biotinylated ligands, from competitive binding assays of N6-[3H]cyclohexyladenosine to rat cerebral cortical membranes
| Compound |
Ki (nM] |
|
|---|---|---|
| No avidin | 1 μM avidin | |
| 2a | 11.4±0.4 | 36 |
| 2b | 18 ±1.7 | 35 |
| 3a | 54 ±2 | <500 |
| 3b | 50±0.4 | <500 |
| 3c | 60 | <500 |
Values are the mean of single experiments done in triplicate or the mean ± SE of 2-6 experiments