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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: CA Cancer J Clin. 2012 May 10;62(5):309–335. doi: 10.3322/caac.20132

FIGURE 8.

FIGURE 8

Immunologic Monitoring. Cross-talk between the tumor and the immune system can be examined in tumor tissue and blood. From tumor tissue, infiltrating cells can be identified. From blood, a variety of assays can be performed, some of which require fresh blood. Others can be performed from frozen/cryopreserved samples and batched for directly compared analysis. TIL indicates tumor-infiltrating lymphocyte; PBMC, peripheral blood mononuclear cells; NK, natural killer; DC, dendritic cell; Treg, regulatory T cells; MDSC, myeloid-derived suppressor cells.