Figure 1. Hazard ratios and 95% confidence intervals (CI) of major chronic disease (A), cardiovascular disease (B), and cancer (C) associated with weekly MET-hours of vigorous-intensity physical activity.
The hazard ratios are adjusted for age, moderate-intensity and low-intensity activities, parental history of MI at or before age 60 years, parental history of cancer at or before age 60 years, smoking, aspirin, vitamin E supplement use, intake of polyunsaturated fat, trans fat, EPA+DHA, and fiber, as well as alcohol intake and pre-existing disease including a diagnosis of diabetes, hypertension, or hypercholesterolemia.