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. Author manuscript; available in PMC: 2013 Aug 7.
Published in final edited form as: Phys Med Biol. 2012 Aug 7;57(15):5035–5055. doi: 10.1088/0031-9155/57/15/5035

Figure 2.

Figure 2

(a) Comparison of σ0 vs. σm as utilized in frame-independent vs. frame-dependent regularizations (13) and (11). To minimize dependence on early-uptake, highly-varying noise levels, only σm values for frames with t>1.5min were averaged to obtain σ0, (b) Plots of resulting image NSD versus frame number for QP-MAP reconstruction using: (i) standard non-regularized MLEM shown as reference, (ii) QP-MAP with frame-independent regularization (MAP (β0)), and (iii) QP-MAP with frame-dependent regularization (MAP (βm)).