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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Neuropharmacology. 2012 Jul 20;64(1):53–64. doi: 10.1016/j.neuropharm.2012.07.020

Fig. 3.

Fig. 3

a) Schematic representation of the method used to separate the different components of the LC sensory-evoked response in single-unit recordings (see text). b) Effects of ATM on LC evoked discharge. The single-unit PSTHs depict two representative neurons per dose. For most neurons, tonic activity was more sensitive to the inhibitory effects of ATM, while largely sparing the excitatory response with a consequent increase in the phasic-to-tonic ratio.