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Bacterial colony forming units (CFU) in blood, peritoneal lavage fluid and lung at 18 hours after CLP in control and TYK2-deficient mice. C57BL/10SnJ (control) and B10.D1-H2q/SgJ (TYK2-defiicent) mice were resuscitated with lactated Ringer’s plus Primaxin (25 mg/kg) immediately after CLP. n = 10 mice per group, the median value is designated.
