Table 4.

Effects of long-term use of ART and other variables on the expression of hBD2 mRNA and its salivary protein levels in HIV-infected subjects

Predictors for the expression	Mean difference between groups
	hBD2 mRNA		Salivary hBD2 protein
	mRNA	P-value*	Unstimulated saliva	P-value*	Stimulated saliva	P-value*
Duration of ART
no vs short-term	130.26	0.228	1.36	0.763	−263.82	0.059
long vs short-term	−32.27	0.635	10.52	0.733	−172.82	<0.001
Duration of HIV infection
5–10 vs < 5 years	−150.19	0.134	8.47	0.684	−103.09	0.006
CD4 count
<200 vs >= 200 cell/cm3	−90.37	0.316	25.79	0.225	8.50	0.468
Viral load
>= 50 vs < 50	−154.40	0.063	−4.69	0.914	162.11	<0.001
Smoking
Yes vs No	64.80	0.160	−6.09	0.653	−22.51	0.535
Alcohol
Yes vs No	−3.10	0.713	−25.8	0.397	−73.30	0.046

^*P-value from ANOVA test, adjusted for other factors