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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: J Hepatol. 2012 Jun 9;57(4):852–859. doi: 10.1016/j.jhep.2012.05.024

Figure 4. TgSOD2 mice exhibit increased susceptibility to MCD-induced SH.

Figure 4

A, serum ALT levels from wild type mice or TgSOD2 mice fed MCD; *p<0.05 vs. WT; **p<0.05 vs. WT+MCD. B, Sirius red staining of liver sections from wild type mice or TgSOD2 mice fed MCD diet. Data are the mean±SD of 3–4 mice. C, myeloperoxidase staining of liver samples from wild type mice or TgSOD2 mice fed MCD diet. D, 3-nitrotyrosine immunoreactivity of wild type mice and TgSOD2 mice fed MCD diet. E, schematic diagram illustrating the effects of superoxide scavenging by SOD mimics with or without GSH depletion.