. Author manuscript; available in PMC: 2013 Sep 15.

Published in final edited form as: Cancer Res. 2012 Jul 17;72(18):4846–4855. doi: 10.1158/0008-5472.CAN-12-1879

Table 2.

Median Survival and Percentage Distribution of Neoplasms in C3H Mice^‡

Group	Number of Mice	Median Survival in weeks (CI)^#	Number of Mice
Group	Number of Mice	Median Survival in weeks (CI)^#	Malignant Neoplasm^† (%)	Non-Hematopoietic Neoplasm^* (%)	Hematopoietic Neoplasm^* (%)	Benign Neoplasm (%)
0 Gy Control	93	100.9 (97.1-109)	47 (51%)	39 (42%)	11 (12%)	46 (49%)
3 Gy Control	170	62 (54.7-70.6)	129 (76%) C:IR p < 0.01	60 (35%) C:IR p = 0.29	75 (44%) C:IR p < 0.01	81 (47%) C:IR p = 0.79
0 Gy Tempol	89	109.1 (107-111)	29 (33%) T:C p = 0.02	27 (30%) T:C p = 0.12	2 (2%) T:C p = 0.02	72 (81%) T:C p < 0.01
3 Gy Tempol	161	95.7 (87.7-98.9)	118 (74%) T:IR-T p < 0.01	75 (47%) T:IR-T p = 0.015	50 (31%) T:IR-T p < 0.01	122 (76%) T:IR-T p =0.43
3 Gy Tempol Delayed	202	84.9 (78.9-92.7)	138 (68%) T:IR T-D p < 0.01	83 (41%) T:IR T-D p = 0.09	66 (33%) T:IR T-D p < 0.01	132 (65%) T:IR T-D p = 0.01

^‡

Statistical comparisons: T:C = 0 Gy T to 0 Gy C; C:IR = 0 Gy C to 3 Gy C; T:IR-T = 0 Gy T to 3 Gy T; T:IR T-D = 0 Gy T to 3 Gy T-D

CI; 95% confidence interval.

^†

Malignant neoplasms include both HN + non-HN.

Percentages in these two categories do not add up to the total percentage of malignant neoplasms because some mice had hematopoietic and non-HN.