Table 1.
Patient Characteristics for Eligible Patients (n=21)
| Characteristics | Number |
|---|---|
| Age (years) | |
| Median (Range) | 12.9 (1.9–21.6) |
|
| |
| Sex | |
| Male: Female | 11: 10 |
|
| |
| Prior Chemotherapy Regimens: | |
| Median (Range) | 4 (1–9) |
|
| |
| Patients with Prior Radiation Therapy | 11 |
|
| |
| Patients with Prior VEGF Blocking Therapy | 6 |
|
| |
| Diagnosis | |
| Embryonal (n=9) | |
|
| |
| Hepatoblastoma | 6 |
|
| |
| Neuroblastoma | 2 |
|
| |
| Wilms tumor | 1 |
|
| |
| Sarcoma (n=7) | |
|
| |
| Ewing sarcoma | 1 |
|
| |
| Alveolar rhabdomyosarcoma | 1 |
|
| |
| Synovial sarcoma | 1 |
|
| |
| Other soft tissue sarcoma (including clear cell, epithelioid, and leiomyosarcoma) | 4 |
|
| |
| Carcinoma (n=3) | |
|
| |
| Adrenocortical | 1 |
|
| |
| Hepatocellular carcinoma | 1 |
|
| |
| Small cell-large cell carcinoma | 1 |
|
| |
| Brain tumor (n=2) | |
|
| |
| Ependymoma | 1 |
|
| |
| Pilocytic astrocytoma | 1 |