Table 1.
Peaks of activations for the brain areas consistently engaged in fMRI studies on moral cognition, theory of mind, and empathy as revealed by ALE meta-analysis
| Macroanatomical location | MNI coordinates | ||
|---|---|---|---|
| x | y | z | |
| ALE meta-analysis of moral cognition | |||
| Ventromedial prefrontal cortex | 4 | 58 | −8 |
| Ventromedial prefrontal cortex | −10 | 42 | −18 |
| Frontopolar cortex | 0 | 62 | 10 |
| Frontopolar cortex | −6 | 52 | 18 |
| Dorsomedial prefrontal cortex | 0 | 54 | 36 |
| Precuneus | 0 | −56 | 34 |
| Right temporo-parietal junction (PGa, PGp) | 62 | −54 | 16 |
| Left temporo-parietal junction (PGa, PGp) | −48 | −58 | 22 |
| Right temporal pole | 54 | 8 | −28 |
| Right middle temporal gyrus | 54 | −8 | −16 |
| Left amygdala | −22 | −2 | −24 |
| Posterior cingulate cortex | −4 | −26 | 34 |
| ALE meta-analysis of theory of mind | |||
| Ventromedial prefrontal cortex | 0 | 52 | −12 |
| Frontopolar cortex | 2 | 58 | 12 |
| Dorsomedial prefrontal cortex | −8 | 56 | 30 |
| Dorsomedial prefrontal cortex | 4 | 58 | 25 |
| Precuneus | 2 | −56 | 30 |
| Right temporo-parietal junction (PGa, PGp) | 56 | −50 | 18 |
| Left temporo-parietal junction (PGa, PGp) | −48 | −56 | 24 |
| Right temporal pole | 54 | −2 | −20 |
| Left temporal pole | −54 | −2 | −24 |
| Right middle temporal gyrus | 52 | −18 | −12 |
| Left middle temporal gyrus | −54 | −28 | −4 |
| Left middle temporal gyrus | −58 | −12 | −12 |
| Right posterior superior temporal sulcus | 50 | −34 | 0 |
| Left posterior superior temporal sulcus | −58 | −44 | 4 |
| Right inferior frontal gyrus (Area 45) | 54 | 28 | 6 |
| Left inferior frontal gyrus | −48 | 30 | −12 |
| Right MT/V5 | 48 | −72 | 8 |
| ALE meta-analysis of empathy | |||
| Dorsomedial prefrontal cortex | 2 | 56 | 18 |
| Dorsomedial prefrontal cortex | −8 | 54 | 34 |
| Right anterior insula | 36 | 22 | −8 |
| Left anterior insula | −30 | 20 | 4 |
| Right inferior frontal gyrus | 50 | 12 | −8 |
| Right inferior frontal gyrus (Area 44) | 54 | 16 | 20 |
| Right inferior frontal gyrus (Area 45) | 50 | 30 | 4 |
| Left inferior frontal gyrus | −44 | 24 | −6 |
| Supplementary motor area (Area 6) | −4 | 18 | 50 |
| Anterior mid-cingulate cortex | −2 | 28 | 20 |
| Rostral anterior cingulate cortex | −4 | 42 | 18 |
| Posterior cingulate cortex | −2 | −32 | 28 |
| Right temporo-parietal junction (PGp) | 52 | −58 | 22 |
| Left temporo-parietal junction (PGa) | −56 | −58 | 22 |
| Right amygdala | 22 | −2 | −16 |
| Right middle temporal gyrus | 54 | −8 | −16 |
| Right posterior superior temporal sulcus | 52 | −36 | 2 |
| Left anterior thalamus | −12 | −4 | 12 |
| Right posterior thalamus | 6 | −32 | 2 |
| Right hippocampus (SUB) | 26 | −26 | −12 |
| Midbrain | 2 | −20 | −12 |
| Right pallidum | 14 | 4 | 0 |