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. 2012 Jan 24;217(4):783–796. doi: 10.1007/s00429-012-0380-y

Table 1.

Peaks of activations for the brain areas consistently engaged in fMRI studies on moral cognition, theory of mind, and empathy as revealed by ALE meta-analysis

Macroanatomical location MNI coordinates
x y z
ALE meta-analysis of moral cognition
Ventromedial prefrontal cortex 4 58 −8
Ventromedial prefrontal cortex −10 42 −18
Frontopolar cortex 0 62 10
Frontopolar cortex −6 52 18
Dorsomedial prefrontal cortex 0 54 36
Precuneus 0 −56 34
Right temporo-parietal junction (PGa, PGp) 62 −54 16
Left temporo-parietal junction (PGa, PGp) −48 −58 22
Right temporal pole 54 8 −28
Right middle temporal gyrus 54 −8 −16
Left amygdala −22 −2 −24
Posterior cingulate cortex −4 −26 34
ALE meta-analysis of theory of mind
Ventromedial prefrontal cortex 0 52 −12
Frontopolar cortex 2 58 12
Dorsomedial prefrontal cortex −8 56 30
Dorsomedial prefrontal cortex 4 58 25
Precuneus 2 −56 30
Right temporo-parietal junction (PGa, PGp) 56 −50 18
Left temporo-parietal junction (PGa, PGp) −48 −56 24
Right temporal pole 54 −2 −20
Left temporal pole −54 −2 −24
Right middle temporal gyrus 52 −18 −12
Left middle temporal gyrus −54 −28 −4
Left middle temporal gyrus −58 −12 −12
Right posterior superior temporal sulcus 50 −34 0
Left posterior superior temporal sulcus −58 −44 4
Right inferior frontal gyrus (Area 45) 54 28 6
Left inferior frontal gyrus −48 30 −12
Right MT/V5 48 −72 8
ALE meta-analysis of empathy
Dorsomedial prefrontal cortex 2 56 18
Dorsomedial prefrontal cortex −8 54 34
Right anterior insula 36 22 −8
Left anterior insula −30 20 4
Right inferior frontal gyrus 50 12 −8
Right inferior frontal gyrus (Area 44) 54 16 20
Right inferior frontal gyrus (Area 45) 50 30 4
Left inferior frontal gyrus −44 24 −6
Supplementary motor area (Area 6) −4 18 50
Anterior mid-cingulate cortex −2 28 20
Rostral anterior cingulate cortex −4 42 18
Posterior cingulate cortex −2 −32 28
Right temporo-parietal junction (PGp) 52 −58 22
Left temporo-parietal junction (PGa) −56 −58 22
Right amygdala 22 −2 −16
Right middle temporal gyrus 54 −8 −16
Right posterior superior temporal sulcus 52 −36 2
Left anterior thalamus −12 −4 12
Right posterior thalamus 6 −32 2
Right hippocampus (SUB) 26 −26 −12
Midbrain 2 −20 −12
Right pallidum 14 4 0

All peaks are assigned to the most probable brain areas as revealed by the SPM Anatomy Toolbox (Eickhoff et al. 2007; Amunts et al. 2005; Geyer 2004; Caspers et al. 2006; Amunts et al. 1999; Eickhoff et al. 2005)